Effect of carrot decoction on the gasric ulcer of white male rats
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Abstract
A study on the effect of carrot decoction to the gastric ulcer of white male rats induced by absolute ethanol 1 ml/200 g orally has been conducted. The study showed that carrot decoction in the doses of 3; 6; and 12 ml/kg could improve the ulcer by amount of 28.41; 46.79; and 75.76 %, respectively. The decoction could also reduce the pH of gastric juice significantly toward the normal level (P<0.01).
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References
Suwandi, U. (1991). Manfaat Beta-Karoten Bagi Kesehatan, Pusat Penelitian dan Pengembangan PT. Kalbe Farma, Jakarta.
Departeman Kesehatan RI, Tanaman Obat Tradisional. Diakses dari https://www.iptek.apjii.or.id, Januari 2008.
Berardi, R.R., Welage, L. S. (2005). Peptic Ulcer Disease, in Dipiro J.T., Talbert R.L.,Yee G.C., Matzke G.R., Wells B.G., Posey L.M, ed: Pharmacotherapy: a Pathophysiologic Approach, 6th ed. USA: McGraw-Hill Companies. p. 630
Price, S. A., & Lorraine. (2006). Patofisiologi Konsep Klinis proses-proses Penyakit (Ed 6). Penerjemah: dr. Brahm U. Pendit, dr. Huriawati Hartanto, dr. Pita Wulansari dan dr.Dewi Asih Mahanani. Jakarta: Penerbit Buku Kedokteran EGC.
Arif, A., & Syamsudin, U. (1995). Farmakologi dan Terapi; Obat Lokal, Edisi IV, Bagian Farmakologi Fakultas Kedokteran Universitas Indonesia: Jakarta.
Guyton, A. C., & Hall. (2006). Medical Physiology 11th ed, 216-245. Phyladelphia: Elsevier Sauders Company.
Anwar, J. (2000). Farmakologi dan Terapi Obat-Obat Saluran Cerna. Jakarta: Hipokrates.
Djuwantoro, D. (1992). Diagnosis dan Pengobatan Tukak Peptik. Cermin Dunia Kedokteran.
Vogel, H. G. (2002). Drugs Discovery and Evaluations Pharmacological assays, 2nd Edition. Berlin, Heidelberg, Germany: Springer-Verlag
Wattimena, J. R. (1982). Lypoprotinemie Experimentale Chez Le Rat, Explo-tation Pharmacocinetique et Pharmacologique as Modele. These Docteur D’Etat Es Sciences, Faculte De Pharmacie, Universite Monpellier I, 236.
Khazaei, M., & Salehi, H. (2006). Protective effect of Falcaria vulgaris extract on ethanol induced gastric ulcer in rat. Iranian Journal of Pharmacology & Therapeutics, 5(1), 43-46.
Alcaraz, M. K., & Jimenez, M. J. (1998). Protective Effect of Hypolaetin-8-Glucosida on The Rat Gastric Mucosa, Proceeding: Plant Flavonoid in Biology and Medicine, 183-186, Strasbourg, France, Alan R. Liss, Inc., New York.
Sceheffler, W. C. (1987). Statistic for The Biological Science, Edisi 2, terjemahan: Drs. Suroso, M., Statistika untuk Biologi, Farmasi, Kedokteran dan Ilmu yang Bertautan. Bandung: Penerbit ITB.