Chemical study of ethyl Acetate fraction of Picrasma Javanica Bl.

Main Article Content

Sri Hainil
Dayar Arbain
Deddi Prima Putra

Abstract

N-1 main compound from ethyl acetate fraction of kayu pahit bark (Picrasma Javanica B1) has been isolated and characterized with colom chromatography and continued with preparative chromatography. According to analized from spectrum data used ultraviolet (UV) spectroscopy, infra red (IR), 1H RMI (Resonansi Magnet Inti), 13 C RMI, Massa , COSY (Correlated Spectroscopy), HSQC (Heteronuclear Single Quantum Correlation), HMBC ( Heteronuclear Multiple Bond Correlation) and literature study showed that the compound of isolation was javanicin A. 

Article Details

How to Cite
Hainil, S., Arbain, D., & Putra, D. P. (2015). Chemical study of ethyl Acetate fraction of Picrasma Javanica Bl. Jurnal Sains Farmasi & Klinis, 2(1), 1–7. https://doi.org/10.29208/jsfk.2015.2.1.41
Section
Research Articles

References

Pedoman Pelaksanaan Uji Klinik Obat Tradisional.,2000, Annonimous, Departemen Kesehatan Republik Indonesia, Direktorat Jendral POM

Arbain, D.,L.T. Byrne, M.V. Sargent, B.W. Skelton, and A.H. White, 1990, "The Alkaloid of Picrasma javanica," Further Studies, Aust.J.Chem., Vol. 43, 433-437

Arbain, D., 2004," Dua Dekade Penelitian Kimia Tumbuhan Sumatera," Bull. Soc. Chem. Nat. Prod. Chem. (Indonesia), 4, 1-12

Djamal, R., 1988, Prinsip-Prinsip Dasar Bekerja dalam Kimia Bahan Alam, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Andalas, Padang

Gritter, R.J., J.M. Bobbit and A.E. Schwarting., 1991, "Introduction to Chromatrography" (Pengantar Kromatografi), terbitan ke-2, diterjemahkan oleh Kosasih Padmawinata, Penerbit ITB, Bandung

Houghton, P.J and A.Rahman., 1998, "Laboratory Handbook for the Fractions of Natural Extracts", Chapman and Hall, London

Marston, A and K. Hostettmann., 1999, "Biological and Chemical Evaluation of Plant Exstracts and Subsequent Isolation Strategy", Vol.43, Kluwer Academic Publishers, Dorddrecht-Boston,London

Ohmoto,T, Koike, K., Mitsunaga., Fukuda, H., Kagei, K., 1989, "Studies on the Constituens of Indonesian Picrasma javanica, Structure of new Quassinoid, Javanicin A, C and D", Chem. Phamr. Bull, 37, 2991-2994

Sastrohamidjojo, H., 1991, Spektroskopi, Penerbit Liberty, Yogyakarta

Silverstein, R.M., G.C. Bassler., T.C. Morrill., 1967, "Spectrometric Identification of Organic Compound", 3 rd ed, John Wiley and Sons, New York

Yosvalina., 1987, Zat Pahit dari Kayu Paik Picrasma javanica, Skripsi Sarjana Kimia, FMIPA, UNAND, Padang