Ethanolic Extract of Dracaena angustifolia Roxb. as Active Cutaneous Anti Anaphylactic on Male White Mice
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Published:
May 5, 2015
Keywords:
Extract Dracaena angustifolia Roxb, anaphylactic, time, diameter, color intensity.
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Abstract
An assay of the active cutaneous anti anaphylactic of the ethanolic extract of the Dracaena angustifolia Roxb. On male white mice has been studied. The assay was done by giving three different doses (100,300, 900 mg per/kg bw). Allergic reaction was induced by giving egg’s albumin as antigen. The anti anaphylactic effect was determined by measurement of the pro long of occurrence time, the dereased in diameter and the color intensity of the blue bump formed by using blue evan’s solution as indicator which was given intravenously. Result indicated the ethanolic extract of Dracaena angustifolia Roxb. (100, 300, 900 mg/kg bw) had significant effect for each dose (p<0.01). The dose of 900 mg per kg body weight showed best effect.
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How to Cite
Aldi, Y., Syafrudin, M., & Elisma, E. (2015). Ethanolic Extract of Dracaena angustifolia Roxb. as Active Cutaneous Anti Anaphylactic on Male White Mice. Jurnal Sains Farmasi & Klinis, 1(2), 150–158. https://doi.org/10.29208/jsfk.2015.1.2.31
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Research Articles
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3. Rustam, E., Indah, A., & Yanwirasti. (2007). Efek antiinflamasi ekstrak etanol kunyit (Curcuma domestica Val.) pada tikus putih jantan galur wistar. Jurnal Sains dan Teknologi Farmasi, Vol. 12, No.2, 2007.
4. Moon PD, BH Lee, HJ Jeong, HJ An, SJ Park and HR Kim, (2007). Use of Scopoletin to Inhibit the Production of Inflammatory Cytokines Through Inhibition of the IκB/NF-Κb Signal Cascade in the Human Mast Cell Line HMC-1, European Journal of Pharmacology. 555(2);218-225.
5. Price KS and RG Hamilton,( 2007). Anaphylactoid Reactions in Two Patients after Omalizu-mab Administration after Successful Long-term Therapy, Allergy Asthma Proc, 28;313–319
6. Dipiro JT, RL Tabert, GC Yee, GR Matzke, BG Wells, LM Posey, (2008). Pharmacotherapy, A Pathophysiologic Approach, 7th Ed. Mc Graw-Hill, Medical Publishing Division, New York. 463-489, 1417-1430.
7. Sukandar EY, (2011). ISO Farmakoterapi, PT ISFI Penerbit, Jakarta, 476-487.
8. Dalimartha, S. (2009). Atlas tumbuhan obat Indonesia. (Edisi 6). Jakarta: Pustaka Bunda, Grup Puspa Swara Anggota IKAPI.
9. Purwanto, M. (1994). Penelitian tanaman obat di beberapa perguruan tinggi di Indonesia. Jakarta. Pusat penelitian dan Pengembangan Farmasi, Departemen Kesehatan RI.
10. Narande J.M,. Anne, W.,Adithya, Y. (2013). Uji efek antiinflamasi ekstrak etanol daun suji (Dracaena angustifolia Roxb). Pharmacon, 3.2. 2302-2493.
11. Subono, B. (2010). Ensilklopedia flora I. Bogor: PT.Kharisma Ilmu.
12. Arfandi. A., & Ratnawulan. D. (2013). Proses pembentukan feofitin dan suji sebagai bahan aktif photosensitizer akibat pemberian variasi suhu. Pillar of physics, Vol.1.58-76
13. Departemen Kesehatan RI. (2008). Farmakope Herbal Indonesia. (Edisi I). Jakarta.
14. Departemen Kesehatan Republik Indonesia. (1989). Materia Medika Indonesia, (Jilid V). Jakarta.
15. Aldi Y, DS Pasaribu dan A Bakhtiar. 2011. Pengaruh Pemberian Kuersetin dari Daun Singkong (Monihot esculenta Crantz) Terhadap Aktivitas dan Kapasitas Fagositosis Makrofag Mencit Putih Jantan. Fakultas Farmasi. Universitas Andalas Padang.
16. Departemen Kesehatan RI. (2000). Parameter standar umum ekstrak tumbuhan obat. Direktorat Jenderal Pengawasan Obat dan Makanan. Direktorat Pengawasan Obat Tradisional. Jakarta.
17. Banerji. A., Aidan. A. L. & Carlos. A. C. (2007). Diphenhydramine versus nonsedating antihistamines for acute allergic reactions: A literature review. Journal allergy asthma proceedings, Vol. 28:416 – 426.
18. Aldi, Y. (2013). Pengaruh Skopoletin dari buah mengkudu (Morinda citrifolia. L.) terhadap IgE,IL4 dan IL10 pada Mencit Putih Jantan Hipersensitivitas Tipe I, Disertasi S3, Pascasarjana Biomedik, Fakultas Kedokteran Universitas Andalas, Padang.
19. Katzung, B.G. (2004). Farmakologi dasar dan klinik, Edisi VIII. Surabaya: Fakultas Kedokteran Universitas Erlangga, Salemba Medika.
20. Mutschler, E. (1993). Dinamika obat. (Edisi V). Penerjemah W.B. Widianto dan A.S.Ranti.Bandung ; ITB.
21. Lankin, J. P. (1972). Alergic disease: diagnosis and managemen. J.B. Lipin Cott Company, Phila Delphia.