Gel formulation of edible bird’s nest (Aerodramus fushipagus) and evaluation of wound healing activity on second-degree burns in mice
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Abstract
The gel formulation from Edible Bird’s Nest (Aerodramus fushipagus) and evaluation of wound healing activity in mice (Mus musculus) has been done. This study aimed to determine the effectiveness of gel formulation from Edible Bird’s Nest with concentrations of 10%, 20% and 30% for second-degree burns in mice. A number of 15 mice were grouped into 5: negative control (base gel), positive control (B), and groups receiving gel formulation in concentrations of 10%, 20%, and 30%. Burns was induced on the back of the mice with 2 cm diameter by using hot metal. The diameter of burns was measured every day for 21 days. Data were analyzed by using two-way ANOVA. The evaluation results show all formulas were homogeneous, stable to temperature and not irritating to the skin. The results showed that the percentage of burn healing between formulations and control were significantly different. The study concludes that all formulas exhibit a wound healing activity as compared with control.
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