Pengaruh Jenis Vaksin Covid-19 pada Kualitas Hidup Terkait Kesehatan (HRQoL) Masyarakat di Kota Padang dan Pariaman

Main Article Content

Boy Andre
Lailaturrahmi Lailaturrahmi
Almahdy A
Armenia Armenia

Abstract

Covid-19 (Corona Virus Disease-2019) merupakan penyakit infeksi yang disebabkan oleh virus coronavirus 2 yang sangat mudah menular dan menyebabkan infeksi pada sistem pernafasan. Vaksinasi Covid-19 adalah salah satu upaya pencehagan penularan, dimana jenis vaksin yang diberikan kepada masyarakat ditetapkan oleh pemerintah. Tujuan penelitian ini adalah menganalisis pengaruh jenis vaksin Covid-19 terhadap kualitas hidup terkait kesehatan (HRQoL) di Kota Padang dan Pariaman. Penelitian dilakukan dengan menyebarkan dalam jaringan kuisioner generik WHOQOL-BREF yang berisi 26 pertanyaan pada bulan Juli – September 2022. Jenis vaksin merupakan variabel independen sedangkan data sosiodemografi responden yang meliputi jenis kelamin, usia, status perkawinan, pekerjaan, kota domisili, pendidikan terakhir, dan penyakit penyerta sebagai covariat. Kuisioner diolah secara statistik menggunakan SPSS versi 26 dengan analisis univariat. Vaksin Covid-19 yang diterima oleh responden yaitu Sinovac dan Sinopharm (inactivated virus), Moderna dan Pfizer (mRNA), serta Astra Zeneca (Non-Replicating Viral Vector). Kuisoner yang diisi secara  lengkap oleh 418 responden didapatkan hasil dimana sebanyak 242 dan 81 responden menyatakan kualitas hidup terkait kesehatan mereka berstatus baik dan sangat baik, sedangakan  93 dan 2 repsonden menyatakan biasa dan buruk. Hasil uji statistik menunjukkan tidak terdapat pengaruh yang signifikan (p>0,05) antara jenis vaksin terhadap ke empat domain pada HRQoL. Namun, terdapat pengaruh yang signifikan (p<0,05) pada covariat yaitu status perkawinan, pekerjaan dan pendidikan terakhir terhadap semua domain pada HRQoL.

Article Details

How to Cite
Andre, B., Lailaturrahmi, L., A, A., & Armenia, A. (2023). Pengaruh Jenis Vaksin Covid-19 pada Kualitas Hidup Terkait Kesehatan (HRQoL) Masyarakat di Kota Padang dan Pariaman. Jurnal Sains Farmasi & Klinis, 9(3), 277–284. https://doi.org/10.25077/jsfk.9.3.277-284.2022
Section
Research Articles

References

. Yuki K, Fujiogi M, Koutsogiannaki S. COVID-19 pathophysiology: A review. Clinical immunology. 2020;215:108427. https://doi.org/10.1016/j.clim.2020.108427

. Almuttaqi AI. Kekacauan Respons terhadap COVID-19 di Indonesia. Thc Insights. 2020;13.

. Rabacal J, Oducado RM, Tamdang K. COVID-19 impact on the quality of life of teachers: A cross-sectional study. Asian Journal for Public Opinion Research. 2020;8(4):478–92. https://doi.org/https://doi.org/10.15206/ajpor.2020.8.4.478

. World Health Organization. WHOQOL : measuring quality of life [Internet]. Geneva PP - Geneva: World Health Organization; Available from: https://apps.who.int/iris/handle/10665/63482

. Algahtani FD, Hassan S-N, Alsaif B, Zrieq R. Assessment of the quality of life during COVID-19 pandemic: A cross-sectional survey from the kingdom of saudi arabia. International Journal of Environmental Research and Public Health. 2021;18(3):847. https://doi.org/10.3390/ijerph18030847.

. Ping W, Zheng J, Niu X, Guo C, Zhang J, Yang H, et al. Evaluation of health-related quality of life using EQ-5D in China during the COVID-19 pandemic. PloS one. 2020;15(6):e0234850. https://doi.org/10.1371/journal.pone.0234850

. Kharshiing KD, Kashyap D, Gupta K, Khursheed M, Shahnawaz MG, Khan NH, et al. Quality of life in the COVID-19 pandemic in India: Exploring the role of individual and group variables. Community mental health journal. 2021;57(1):70–8. https://doi.org/10.1007/s10597-020-00712-6.

. Epifanio MS, Andrei F, Mancini G, Agostini F, Piombo MA, Spicuzza V, et al. The impact of COVID-19 pandemic and lockdown measures on quality of life among Italian general population. Journal of Clinical Medicine. 2021;10(2):289. https://doi.org/10.3390/jcm10020289.

. Hodgson SH, Mansatta K, Mallett G, Harris V, Emary KRW, Pollard AJ. What defines an efficacious COVID-19 vaccine? A review of the challenges assessing the clinical efficacy of vaccines against SARS-CoV-2. The lancet infectious diseases. 2021;21(2):e26–35. https://doi.org/10.1016/S1473-3099(20)30773-8

. Shi Y, Wang G, Cai X, Deng J, Zheng L, Zhu H, et al. An overview of COVID-19. Journal of Zhejiang University-SCIENCE B. 2020;21(5):343–60. https://doi.org/10.1631/jzus.B2000083.

. Jeyanathan M, Afkhami S, Smaill F, Miller MS, Lichty BD, Xing Z. Immunological considerations for COVID-19 vaccine strategies. Nature Reviews Immunology. 2020;20(10):615–32. https://doi.org/10.1038/s41577-020-00434-6.

. Sherman SM, Smith LE, Sim J, Amlôt R, Cutts M, Dasch H, et al. COVID-19 vaccination intention in the UK: results from the COVID-19 vaccination acceptability study (CoVAccS), a nationally representative cross-sectional survey. Human vaccines & immunotherapeutics. 2021;17(6):1612–21. https://doi.org/10.1080/21645515.2020.1846397.

. TEndarti AT. Kualitas Hidup Kesehatan: Konsep, Model, dan Penggunaan. J Ilm Kesehat. 2015;7(2):97–108. Available from: https://lp3m.thamrin.ac.id/upload/jurnal/JURNAL-1519375940.pdf

. WHOQOL-BREF. WHOQOL-BREF : introduction, administration, scoring and generic version of the assessment : field trial version, December. World Health Organization. 1996. p. 1–16.

. World Health Organization. The World Health Organization Quality of Life (WHOQOL)-BREF. Geneva; 2004.

. Gondodiputro S, Wiwaha G, Lionthina M, Sunjaya DK. Reliability and validity of the indonesian version of the world health organization quality of life-old (Whoqol-old): A rasch modeling. Medical Journal of Indonesia. 2021;30(2):143–51. https://doi.org/10.13181/mji.oa.215065

. Zintel S, Flock C, Arbogast AL, Forster A, von Wagner C, Sieverding M. Gender differences in the intention to get vaccinated against COVID-19: a systematic review and meta-analysis. Journal of Public Health (Germany). 2022;(0123456789). https://doi.org/10.1007/s10389-021-01677-w

. Kementerian Kesehatan Republik Indonesia. Vaksinasi COVID-19 Berdasarkan Provinsi dan Kabupaten/ Kota. 2022.

. CDC. Sociodemographic Factors Associated with Receipt of COVID-19 Vaccination and Intent to Definitely Get Vaccinated, Adults aged ≥18 Years — Household Pulse Survey, United States, April 28–May 10, 2021. 2021.

. Perhimpunan Dokter Spesialis Penyakit Dalam Indonesia (PAPDI). Rekomendasi PAPDI tentang Pemberian Vaksinasi COVID-19 pada Pasien dengan Penyakit Penyerta/ Komorbid (Revisi 18 Maret 2021). 2021.

. Purba FD, Hunfeld JAM, Iskandarsyah A, Fitriana TS, Sadarjoen SS, Passchier J, et al. Quality of life of the Indonesian general population: Test-retest reliability and population norms of the EQ-5D-5L and WHOQOL-BREF. PLoS ONE. 2018;13(5):1–20. https://doi.org/10.1371/journal.pone.0197098

. Gondodiputro S, Rizki Hidayati A, Rahmiati L. Gender, Age, Marital Status, and Education as Predictors to Quality of Life in Elderly: WHOQOL-BREF Indonesian Version. International Journal of Integrated Health Sciences. 2018;6(1):36–41. https://doi.org/10.15850/ijihs.v6n1.1201

. Beatty AL, Peyser ND, Butcher XE, Cocohoba JM, Lin F, Olgin JE, et al. Analysis of COVID-19 vaccine type and adverse effects following vaccination. JAMA network open. 2021;4(12):e2140364–e2140364. https://doi.org/10.1001/jamanetworkopen.2021.40364

. Wei Y, Wang Y, Liu L, Zha Y, Yang Y, Wang Y, et al. Analysis of Adverse Effects of COVID-19 Vaccines Experienced by Healthcare Workers at Guizhou Provincial Staff Hospital, China. Vaccines. 2022;10(9):1449. https://doi.org/10.3390/vaccines10091449.

. Yorgason JB, Stott KL. Physical Health and Marital Status. The Encyclopedia of Adulthood and Aging. 2015;1–5.

. Hughes ME, Waite LJ. Marital biography and health at mid-life. Journal of health and social behavior. 2009;50(3):344–58. https://doi.org/10.1177/002214650905000307.

. Tatangelo G, McCabe M, Campbell S, Szoeke C. Gender, marital status and longevity. Maturitas. 2017;100:64–9. https://doi.org/10.1016/j.maturitas.2017.03.002

. Štěpánek L, Janošíková M, Nakládalová M, Ivanová K, Macík J, Boriková A, et al. Motivation for COVID-19 Vaccination in Priority Occupational Groups: A Cross-Sectional Survey. International journal of environmental research and public health. 2021;18(21):11726. https://doi.org/10.3390/ijerph182111726

. Corace KM, Srigley JA, Hargadon DP, Yu D, MacDonald TK, Fabrigar LR, et al. Using behavior change frameworks to improve healthcare worker influenza vaccination rates: a systematic review. Vaccine. 2016;34(28):3235–42. https://doi.org/10.1016/j.vaccine.2016.04.071.

. Betsch C. Innovations in communication: the Internet and the psychology of vaccination decisions. Eurosurveillance. 2011;16(17):19849. https://doi.org/https://doi.org/10.2807/ese.16.17.19849-en

. Baum S, Ma J, Payea K. Education Pays, 2013: The Benefits of Higher Education for Individuals and Society. Trends in Higher Education Series. College Board. 2013;

. Turhan Z, Dilcen HY, Dolu İ. The mediating role of health literacy on the relationship between health care system distrust and vaccine hesitancy during COVID-19 pandemic. Current psychology. 2022;41(11):8147–56. https://doi.org/10.1007/s12144-021-02105-8

. Umakanthan S, Bukelo MM, Bukelo MJ, Patil S, Subramaniam N, Sharma R. Social Environmental Predictors of COVID-19 Vaccine Hesitancy in India: A Population-Based Survey. Vaccines. 2022;10(10):1749. https://doi.org/https://doi.org/10.3390/vaccines10101749

. Sallis JF, Cerin E, Conway TL, Adams MA, Frank LD, Pratt M, et al. Physical activity in relation to urban environments in 14 cities worldwide: a cross-sectional study. The lancet. 2016;387(10034):2207–17. https://doi.org/10.1016/S0140-6736(15)01284-2.

. Goenka S, Andersen LB. Our health is a function of where we live. The lancet. 2016;387(10034):2168–70. https://doi.org/10.1016/S0140-6736(16)00348-2

. Lin CY, Fan CW, Ahorsu DK, Lin YC, Weng HC, Griffiths MD. Associations between vaccination and quality of life among Taiwan general population: A comparison between COVID-19 vaccines and flu vaccines. Human Vaccines and Immunotherapeutics. 2022;18(5). https://doi.org/10.1080/21645515.2022.2079344

. Ayoubkhani D, Bermingham C, Pouwels KB, Glickman M, Nafilyan V, Zaccardi F, et al. Trajectory of long covid symptoms after covid-19 vaccination: community based cohort study. The BMJ. 2022;1–11. https://doi.org/10.1136/bmj-2021-069676

. Blay SL, Marchesoni MSM. Association among physical, psychiatric and socioeconomic conditions and WHOQOL-Bref scores. Cadernos de Saúde Pública. 2011;27(4):677–86. https://doi.org/10.1590/s0102-311x2011000400007