Formulation and Evaluation of Edible Film from Basil Leaves Extract (Ocimum americanum L.) as Mouth Freshener

Main Article Content

Fifi Harmely
Ellyza Nasrul
Salman Umar
Erizal Zaini
Yufri Aldi

Abstract

A research on formulation of edible film from basil leaves extract as mouth freshener has been done. The extract of basil leaves were used in various concentrations which are 2.5%, 5% and 7.5%. The products were evaluated for some parameters such as organoleptic, friability, drying shrinkage, pH, thickness, flavonoid contents and respondents preference. The results of evaluation showed that edible filmsfrom basil leaves extract meet requirements as required by Standard Nasional Indonesia (SNI) and have such quality as product in the market. Statistical analysis using Kruskal Wallis test showed that respondents preferred for the F0 formulation in term of their appearance and taste while as mouth freshener, respondents preferred the F3 formulation.

Article Details

How to Cite
Harmely, F., Nasrul, E., Umar, S., Zaini, E., & Aldi, Y. (2018). Formulation and Evaluation of Edible Film from Basil Leaves Extract (Ocimum americanum L.) as Mouth Freshener. Jurnal Sains Farmasi & Klinis, 5(2), 88–93. https://doi.org/10.25077/jsfk.5.2.88-93.2018
Section
Research Articles

References

Abdou, H. M., 1989, Dissolution, Bioavaibility and Bioequivalence, Mark Publishing Company Easton: Pennsylavania

Bahirah, A, 2016. Kajian Sifat Fisikokimia Dispersi Padat Irbesartan Dengan Poloxamer 188. STIFI. Padang.

Carr, A., McCall, M. & Frei, B., 2000. Oxidation of LDL myeloperoxidase and reactive nitrogen species : reaction pathways and antioxidant protection. Arterioscler Thromb Vasc Biol. ,Hal.1716.

Chawla, G. & Bansal, A.K., 2007. A comparative assessment of solubility advantage from glassy and crystalline forms of a water-insoluble drug. Eur. J. Pharm. Sci. 32: 45-57.

Dipiro & Joseph.T., 2005. Pharmacotherapy: A Pathophysiologic Appoach, Sixth Edition. The McGraw-Hill Companies, Inc: USA.

Goodman & Gilman, 2010.Manual Farmakologi dan Terapi (hal 507). Penerbit buku kedokteran EGC. Jakarta.

Kumar, , G. A., Ram, K. C & CH. C., 2011, Enhancement of Solubility and Dissolution Rate of Irbesartan by Solid Dispersion Technique. Asian, Journal of Pharmaceutical and Clinical Research, vol.4, issue 2, ISSN 0974-2441.

Shargel, L., Wu-Pong, S., and Yu, A.B.C., 2012, Biofarmasetika dan Farmakokinetika Terapan. Terjemahan oleh Budi Suprapti, Edisi Kelima, Airlangga University Press: Surabaya

Sargowo & Djanggan., 2015. Disfungsi Sel Endotel. Universitas Brwijaya Press (Ub Press),Malang.

Sharma, R. Monika., Rajeev Garg., G.G. Gupita. 2013. Formulation and evaluation of Solid Dispersion of Atrovastatin Calsium. Journal of Pharmaceutical and Scientific Innovation., vol. 2. 4: 73-81.

Ghareeb,Alla, A. A., Ahmed A. H. and Mohammed I. N., 2009. Kneading Technique for Preparation of Binary Solid Dispersion of Meloxicam withPoloxamer 188, AAPS PharmSciTech., vol.10, no.4.

Hang, Y., Myung-Kwan C. & Hoo-Kyun, C., 2017. No Title. Preparation and Characterization of Piroxicam/Poloxamer Solid Dispersion Prepared by Melting Method and Solvent Method,J Korean Pharm Sci., 37:1–5.

Wahyudi,.F 2016. Uji Efek Antihipertensi Dari Dispersi Padat Irbesartan Dengan Pembawa Poloxamer 188 Dan Pembawa Polivinil Pirolidon (PVP) K-30 Pada Tikus Putih Jantan, STIFI. Padang.