In-vitro Sun Protecting Factor of Rice Bran Oil and Its Formulation as Compact Powder

Armini Syamsidi, Evi Sulastri, Yusriadi Yusriadi, Pramita Putri, Nuur Aanisah
10.25077/jsfk.10.1.54-61.2023

Abstrak


This study aims to determine the effective concentration of rice bran oil which can protect against ultraviolet (UV) rays as well as formulate it in compact powder preparation followed by determination of its Sun Protecting Factor (SPF) value. Rice bran samples were extracted using the Soxhlet extraction method with n-hexane: ethanol (1:1) as the solvent. Further identification of the γ-oryzanol in rice bran oil was carried out using TLC silica gel GF254 with eluent of n-hexane:ethyl acetate (3:1). The obtained γ-oryzanol in rice bran oil was used as the ingredient to develop the compact powder which is made into five formulas with 0,05 %-0,25 % concentration. All formulas were characterized, including homogeneity, adhesion and crack test. UV-Visible spectrophotometry was used to determine the SPF value of rice bran oil and its compact powder. The identification results demonstrated a positive presence of the chemical γ-oryzanol in the rice bran oil. At concentrations of 500, 1000, 1500, 2000, and 2500 ppm, rice bran oil may protect against UV rays with SPF values ranging from 1.741 to 11.884. The result showed that all formulas dispersed homogeneously, performed well in terms of compactness, and had no breaks or cracks discovered. Meanwhile, the SPF values of all formulas are found to be 1.390 and 1.274. The results indicate that the SPF values are shallow and are included in the minimal SPF category (2-4) in protecting against UV rays.


Kata Kunci


rice bran; γ-oryzanol; compact powder; SPF

Teks Lengkap:

PDF (English)

Referensi


. Kale S, Sonawane A, Ansari A, Ghoge P, Waje A. Formulation and in- vitro determination of sun protection factor of Ocimum basilicum, Linn. leaf oils sunscreen cream. Int J Pharm Pharm Sci. 2010;

. Sambandan DR, Ratner D. Sunscreens: An overview and update. J Am Acad Dermatol. 2011;64(4):748–58. https://doi.org/10.1016/j.jaad.2010.01.005

. Bernardi DS, Pereira TA, Maciel NR, Bortoloto J, Viera GS, Oliveira GC, et al. Formation and stability of oil-in-water nanoemulsions containing rice bran oil: In vitro and in vivo assessments. J Nanobiotechnology. 2011; https://doi.org/10.1186/1477-3155-9-44

. Juliano C, Cossu M, Alamanni MC, Piu L. Antioxidant activity of gamma-oryzanol: Mechanism of action and its effect on oxidative stability of pharmaceutical oils. Int J Pharm. 2005;299(1–2):146–54. https://doi.org/10.1016/j.ijpharm.2005.05.018

. Sapino S, Carlotti ME, Cavalli R, Ugazio E, Berlier G, Gastaldi L, et al. Photochemical and antioxidant properties of gamma-oryzanol in beta-cyclodextrin-based nanosponges. J Incl Phenom Macrocycl Chem. 2013;75(1–2):69–76. https://doi.org/10.1007/s10847-012-0147-3

. Nagendra Prasad MN NP, KR S, Khatokar M S. Health Benefits of Rice Bran - A Review. J Nutr Food Sci. 2011; https://doi.org/10.4172/2155-9600.1000108

. Mohiuddin AK. An extensive review of face powders: Functional uses and formulations. Int J Pharm Pharm Sci. 2019;1(1):1–12. https://doi.org/10.5281/zenodo.3547001

. Mohiuddin AK, Trust MNM. Face Powders : Formulation Considerations. 2019;1–29.

. Gabriella B, Kenneth S. A. Introduction To Cosmetic Formulation and Technology. Wiley. 2015. https://doi.org/10.1007/s13398-014-0173-7.2

. Estefan G, Sommer R, Ryan J. Methods of Soil , Plant , and Water Analysis : A manual for the West Asia and North. Int Cent Agric Res Dry Areas ICARDA@cgiar.org. 2013; https://doi.org/10.1038/modpathol.3800701

. Pandey R, Shrivastava SL. Comparative evaluation of rice bran oil obtained with two-step microwave assisted extraction and conventional solvent extraction. J Food Eng. 2018; https://doi.org/10.1016/j.jfoodeng.2017.09.009

. Mariod A, Ismail M, Abd Rahman NF, Matthaus B. Stability of rice bran oil extracted by SFE and soxhlet methods during accelerated shelf-life storage. Grasas y Aceites. 2014; https://doi.org/10.3989/gya.109413

. Khunkitti W, Satthanakul P, Waranuch N, Pitaksuteepong T, Kitikhun P. Method for screening sunscreen cream formulations by determination of in vitro SPF and PA values using UV transmission spectroscopy and texture profile analysis. J Cosmet Sci. 2014;

. Rejeki S. The SPF Value Determination of Extract and Sunscreen Lotio of Lime Rind Extract by Spektrofometri UV-Vis Method. J Farm (Journal Pharmacy). 2018; https://doi.org/10.37013/jf.v1i1.58

. Jarupinthusophon S, Anurukvorakun O. Development of jasmine rice flour properties as a safe and efficient ingredient for compact powder. Appl Sci. 2021;11(1):1–12. https://doi.org/10.3390/app11010248

. FDA. Sunscreen drug products for over-the-counter human use [Internet]. Department of Health and Human Services. 2022. Available from: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=352&showFR=1#:~:text=The concentration of each active,the combination multiplied by 2

. Sakunpak A, Suksaeree J, Monton C, Pathompak P, Kraisintu K. Quantitative analysis of γ-oryzanol content in cold pressed rice bran oil by TLC-image analysis method. Asian Pac J Trop Biomed. 2014;4(2):119–23. https://doi.org/10.1016/S2221-1691(14)60219-7

. Dutra EA, Da Costa E Oliveira DAG, Kedor-Hackmann ERM, Miritello Santoro MIR. Determination of sun protection factor (SPF) of sunscreens by ultraviolet spectrophotometry. Rev Bras Ciencias Farm J Pharm Sci. 2004;40(3):381–5. https://doi.org/10.1590/S1516-93322004000300014

. Min DB, Boff JM. Chemistry and reaction of singlet oxygen in foods. Compr Rev Food Sci Food Saf. 2002;1(2):58–72. https://doi.org/10.1111/j.1541-4337.2002.tb00007.x

. Park JW, Jang EY, Kim JY, Yi BR, Kim MJ, Park KW, et al. Effects of visible light irradiation on the oxidative stability in rice bran. J Cereal Sci. 2013;58(1):178–81. https://doi.org/10.1016/j.jcs.2013.05.004

. Montenegro L, Santagati LM. Use of vegetable oils to improve the sun protection factor of sunscreen formulations. Cosmetics. 2019;6(2). https://doi.org/10.3390/COSMETICS6020025




DOI: https://doi.org/10.25077/jsfk.10.1.54-61.2023

Article Metrics

Abstract view : 371 times
PDF (English) view/download : 275 times

Bookmark and Share


JSFK (Jurnal Sains Farmasi & Klinis) (J Sains Farm Klin) | p-ISSN: 2407-7062 | e-ISSN: 2442-5435

Diterbitkan oleh Fakultas Farmasi Universitas Andalas bekerjasama dengan Ikatan Apoteker Indonesia - Daerah Sumatera Barat 

      

 JSFK is licensed under Creative Commons Attribution-ShareAlike 4.0 International License.