Obat Off-Label Pada Anak di Pelayanan Rawat Jalan Klinik Pratama Swasta Kabupaten Sleman Yogyakarta

Ndaru Setyaningrum, Haudatul Khamsani, Rosita Mulyawati

Abstrak


Penelitian ini dilakukan untuk mengetahui peresepan obat off label pada anak di pelayanan rawat jalan klinik pratama swasta di Kabupaten Sleman. Penelitian dilakukan secara retrospektif dengan pengambilan data berdasarkan rekam medis anak tahun 2015. Subjek penelitian merupakan rekam medis anak dengan batasan usia di bawah 11 tahun. Jumlah populasi selama periode penelitian adalah 119 rekam medis. Total jumlah penggunaan obat sebanyak 343 obat. Hasil kajian penggunaan obat off-label ditemukan 107 kasus (31,19%). Kategori obat off-label berturut – turut dari prevalensi tertinggi adalah off-label dosis 53 kasus (15,45%); off-label usia 40 kasus (11,66%); off-label indikasi 13 kasus (3,79%); dan off-label cara pemberian 1 (0,29%). Rentang usia anak 1 – 23 bulan ditemukan off-label sebanyak 14 anak (11,76%); usia 2 - <5 tahun dan 5 – 11 tahun masing – masing 38 anak (31,92%). Jenis obat off-label paling dominan adalah klorfeniramin maleat kategori subdosis dan off-label usia. Hasil penelitian ini mendorong perhatian lebih tenaga kesehatan terhadap efikasi dan risiko penggunaan obat off-label pada anak

Kata Kunci


off-label; peresepan; anak; klinik pratama swasta

Teks Lengkap:

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Referensi


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DOI: https://doi.org/10.25077/jsfk.6.1.37-45.2019

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